Brunner-Type Glands in Regional Enteritis

Summary 1.A study of a series of cases of regional enteritis confirms observations that aberrant Brunner-type glands are sometimes encountered in the resected ileum in this disease. Such changes were found in 16 of 34 cases studied. 2.A microscopic description of these aberrant glands is presented with a discussion of possible etiologic factors. 3.A clinical application in prognosis is suggested, since the subsequent recurrence rate was 67 per cent in the group of 16 cases of regional ileitis showing Brunner-type gland development in the resected ileum; this is contrasted with the entire lack of recurrences in 18 cases of regional ileitis exhibiting no Brunner-type glands in the resected area.