Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

Nicola J. Armstrong,Karen A. Mather,Muralidharan Sargurupremraj,Maria J. Knol,Rainer Malik,Claudia L. Satizabal,Lisa R. Yanek,Wei Wen,Vilmundur Gudnason,Nicole Dueker,Lloyd T. Elliott,Edith Hofer,Joshua C. Bis,Neda Jahanshad,Shuo Li,Mark A Logue,Michelle Luciano,Markus Scholz,Albert V. Smith,Stella Trompet,Dina Vojinovic,Rui Xia,Fidel Alfaro-Almagro,David Ames,Najaf Amin,Philippe Amouyel,Alexa Beiser,Henry Brodaty,Ian J. Deary,Christine Fennema-Notestine,Piyush G. Gampawar,Rebecca F. Gottesman,Ludovica Griffanti,Clifford R. Jack,Mark Jenkinson,Jiyang Jiang,Brian G Kral,John B. J. Kwok,Leonie Lampe,David C. Liewald,Pauline Maillard,Jonathan Marchini,Mark E. Bastin,Bernard Mazoyer,Lukas Pirpamer,Jose R. Romero,Gennady V. Roshchupkin,Peter R. Schofield,Matthias L. Schroeter,David J. Stott,Anbupalam Thalamuthu,Julian N. Trollor,Christophe Tzourio,Jeroen van der Grond,Meike W. Vernooij,Veronica Witte,Margaret J. Wright,Qiong Yang,Zoe Morris,Siggi Siggurdsson,Bruce M. Psaty,Arno Villringer,Helena Schmidt,Asta Håberg,Cornelia M. van Duijn,J. Wouter Jukema,Martin Dichgans,Ralph L. Sacco,Clinton B. Wright,William S. Kremen,Lewis C. Becker,Paul M. Thompson,Thomas H. Mosley,Joanna M. Wardlaw,M. Arfan Ikram,Hieab H.H. Adams,Sudha Seshadri,Perminder S. Sachdev,Stephen M. Smith,Lenore J. Launer,William T. Longstreth,Charles DeCarli,Reinhold Schmidt,Myriam Fornage,Stéphanie Debette,Paul A. Nyquist

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

2020

Nicola J. Armstrong
Karen A. Mather
Muralidharan Sargurupremraj
Maria J. Knol
Rainer Malik
Claudia L. Satizabal
Lisa R. Yanek
Wei Wen
Vilmundur Gudnason
Nicole Dueker
Lloyd T. Elliott
Edith Hofer
Joshua C. Bis
Neda Jahanshad
Shuo Li
Mark A Logue
Michelle Luciano
Markus Scholz
Albert V. Smith
Stella Trompet
Dina Vojinovic
Rui Xia
Fidel Alfaro-Almagro
David Ames
Najaf Amin
Philippe Amouyel
Alexa Beiser
Henry Brodaty
Ian J. Deary
Christine Fennema-Notestine
Piyush G. Gampawar
Rebecca F. Gottesman
Ludovica Griffanti
Clifford R. Jack
Mark Jenkinson
Jiyang Jiang
Brian G Kral
John B. J. Kwok
Leonie Lampe
David C. Liewald
Pauline Maillard
Jonathan Marchini
Mark E. Bastin
Bernard Mazoyer
Lukas Pirpamer
Jose R. Romero
Gennady V. Roshchupkin
Peter R. Schofield
Matthias L. Schroeter
David J. Stott
Anbupalam Thalamuthu
Julian N. Trollor
Christophe Tzourio
Jeroen van der Grond
Meike W. Vernooij
Veronica Witte
Margaret J. Wright
Qiong Yang
Zoe Morris
Siggi Siggurdsson
Bruce M. Psaty
Arno Villringer
Helena Schmidt
Asta Håberg
Cornelia M. van Duijn
J. Wouter Jukema
Martin Dichgans
Ralph L. Sacco
Clinton B. Wright
William S. Kremen
Lewis C. Becker
Paul M. Thompson
Thomas H. Mosley
Joanna M. Wardlaw
M. Arfan Ikram
Hieab H.H. Adams
Sudha Seshadri
Perminder S. Sachdev
Stephen M. Smith
Lenore J. Launer
William T. Longstreth
Charles DeCarli
Reinhold Schmidt
Myriam Fornage
Stéphanie Debette
Paul A. Nyquist

Background and Purpose: Periventricular white matter hyperintensities (WMH; PVWMH) and deep WMH (DWMH) are regional classifications of WMH and reflect proposed differences in cause. In the first st...

Keywords:

Neuroimaging
Genetic variation
Medicine
Deep white matter hyperintensities
Periventricular white matter hyperintensities
Physical therapy
White matter
Pathology

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