1α,2α-epoxyscillirosidine, the main toxic principle of Homeria glauca (Wood and Evans) N.E. Br.

Abstract The structure of the main toxic principle of Homeria glauca (Wood and Evans) N.E. Br. has been established as 1α,2α-epoxyscillirosidine (II; R = H) by its degradation to a 1,4-dien-3-one also prepared from the known scillirosidine (I). NMR and CD measurements were used to determine the full stereochemistry.