Hemangioma of the Spleen with Thrombocytopenia and Fibrinogen Deficiency

Summary A case of giant splenic hemangioma associated with thrombocytopenia and fibrinogen deficiency is described. The case presented clinically with severe bleeding and splenomegaly. Treatment with prednisone and transfusions of fresh blood and fibrinogen, was unsuccessful in controlling the hemorrhage. Following splenectomy, the patient improved considerably, the bleeding tendency disappeared and the blood findings became normal. The relationship between giant heman-giomata, either visceral or cutaneous, and the disturbed mechanisms of blood clotting is discussed.