Obstacles to Pediatric Clinical Trial Enrollment: Why Parents Refuse; Findings from the Clinical Trials Transformation Initiative

Purpose: Describe recommendations for improving pediatric trial enrollment based on qualitative data gathered from interviews with parents. Methods: Between 2014 and 2015, 24 in-depth qualitative, 30-60 minute telephone interviews were conducted to explore parent perspectives on factors impacting their decision to enroll their child in clinical trials. Participants were parents recruited through a national database and at Duke University whose children were offered an opportunity to participate in a clinical trial, including 19 whose children participated in at least one clinical trial and 5 who declined an opportunity for …