Clinical case report on treatment of Listeria monocytogenes meningoencephalitis: Intrathecal injection

Listeria monocytogenes meningoencephalitis (LMM) is an infectious disease caused by the infection of the central nervous system by listeria monocytogenes (LM). It has a fast progression, high misdiagnosis rate, and a poor prognosis. The main susceptible populations are immunocompromised or defective. The diagnosis was mainly dependent on the bacteriology tests of body fluid. Nowadays, early application of sensitive antibiotics is the main treatment method. Bacteriological examination takes a long time and lacks specific clinical manifestations, which are important factors affecting early diagnosis and prognosis. This study reports the process of diagnosis and treatment of LMM, which is misdiagnosed because of its atypical clinical manifestations, so as to provide reference for the diagnosis and treatment of similar cases in the future.