PD33-02 IS IT IMPOSSIBLE FOR WOMEN WITH LOWER URINARY TRACT SYMPTOMS TO MAINTAIN ADHERENCE TO ANTICHOLINERGIC AGENTS?

INTRODUCTION AND OBJECTIVES: Vaginal delivery may cause trauma to pelvic floor muscle (PFM). Several authors attribute urogynecological symptoms that appear during the climacteric period to PFM dysfunction secondary to pregnancy and delivery. This neuromuscular injury may cause weakness in pelvic support structures. The aim of this study was to evaluate the impact of parity and mode of delivery on PFM strength in healthy continent women. METHODS: Hundred forty healthy continents women were divided into 4 groups according to age: G1 (n 1⁄4 34) 30-40 years old; G2 (n 1⁄4 38) 41-50 years old; G3 (n 1⁄4 35) 51-60 years old and G4 (n 1⁄4 33) over 60 years old. The following parameters were analyzed: obstetric and gynecological data assessed by clinical questionnaire; body mass index (BMI); subjective evaluation of PFM strength assessed by transvaginal digital palpation (TDP) and objective evaluation of PFM using perineometer. RESULTS: BMI was significantly higher in G4 compared to G1 group (Table 1). The number of pregnancies was significantly higher in G4 compared to G2 (Table 1). The number of vaginal deliveries was significantly higher in G4 compared to G1 and G3 (Table1). There was a positive linear relationship between age and BMI (r 1⁄4 0,215, p 1⁄4 0,011). There was no statistical correlation among different groups in PFM strength assessed by TDP and perineometer. There was not linear relationship between PFM strength and number of pregnancies (r1⁄4 0.70 p1⁄4 0.409) and vaginal deliveries (r1⁄4 -0.026 p1⁄40.758). CONCLUSIONS: These data demonstrate that despite the increase in BMI, number of pregnancies and vaginal deliveries with aging, these parameters did not impact on PFM strength in continent women.