Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity

The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobial, anti-cancer targeting human carbonic anhydrase (CA) and DNA binding activities.