Clinical value of endoscopic submucosal dissection for superficial hypopharyngeal neoplasm (with video)

Objective To evaluate the safety and efficacy of endoscopic submucosal dissection(ESD)for superficial hypopharyngeal neoplasm. Methods Clinicopathological data of 9 patients, who received ESD for superficial hypopharyngeal neoplasm in Zhongshan Hospital affiliated to Fudan University from September 2015 to March 2018, were retrospectively analyzed. Results Nine patients including 7 males and 2 females with mean age of 61.2 years (48-80 years)were included. The mean diameter of lesions was 16.3 mm (5-27 mm), and the mean operation time was 52.2 min(30-90 min). No bleeding, perforation, emphysema or dyspnea during or after ESD occurred. The mean length of hospitalization was 4.6 days (3-7 days). Pathology indicated 1 high grade intraepithelial neoplasia and 8 squamous cell cancer, and all cases of squamous cell cancer were constrained within lamina propria. One patient had positive horizontal margin and received radiotherapy. No recurrence, metastasis or stenosis was found during 10.2 months (3-29 months)of follow-up. Conclusion ESD is a safe and effective option for superficial hypopharyngeal neoplasm. Key words: Endoscopy; Hypopharyngeal neoplasms; Endoscopic submucosal dissection