Spectral Regularities of Viscoelastic Parameters of Whole Blood Exposed to Periodic Shear Stress.

Theoretic and experimental study of viscoelastic properties of the whole blood exposed to shear stress was carried out with acoustic resonance method based on the measurement of gain-frequency characteristics of resonating needle in an ARP-01M piezoelectric thromboelastograph (Mednord). The study revealed regularities in the changes of viscoelastic parameters of the whole blood within 0-80 kHz frequency range of shear vibrations. In this frequency range, the elastic (storage) modulus G' reflecting blood elasticity increased with frequency and significantly contributed to the complex viscosity coefficient. The revealed gain-frequency regularities open the vista to employ the acoustic resonance method to determine the viscoelastic parameters of the whole blood and their coagulation-induced changes in the wide frequency range of shear vibrations.