Фармакогенетика и клинические исследования: точки соприкосновения

Pharmacogenetics and clinical trials developed independently for decades. Nowadays it becomes apparent that genetic testing and the pharmacogenetic are necessary for the clinical studies to ensure effective and safe treatment. At the initial stages of clinical trials of the experimental groups we exclude volunteers and/or patients who have pharmacokinetic and pharmacodynamic differences by genetic testing. Conversely, later phases of clinical trials we to examine the efficacy and safety in the samples of patients with genetically determined differences from the norm.