HYPERTHERMIA EFFECT OF RADIOFREQUENCY RADIATION ON POROUS SILICON NANOPARTICLES DISPERSED IN AQUEOUS SOLUTIONS

Aqueous suspensions of porous silicon (PSi) nanoparticles (NPs) were subjected to electromagnetic radiofrequency (RF) radiation of frequency 27 MHz. It was found that under the RF radiation the suspensions exhibited strong heating effect, while water was not remarkably heated at the induced intensities. The achieved heating rate for concentration ~1 mg/mL under RF irradiation at intensity of 5 W/cm 2 was about 10 K/min and after 5 minutes of the irradiation the temperature rose up to 65-70 o C. The heating rate was linearly depended on the PSi concentration and was compatible with that for gold nanoparticles. The observed hyperthermia effect was utilized for destruction of Lewis lung carcinoma cells in vivo .