Detection of the plasmid-mediated mcr-1 gene in clinical KPC-2-producing Escherichia coli isolates in Brazil
2017
This study reports the first detection of mcr-1 in KPC-2-producing
clinical E. coli isolates in Brazil and emphasises the importance of
microbiological and molecular surveillance to avoid the spread of
these genes in this country. The detection of successful E. coli clones
containing mcr-1 and β-lactamase genes in conjugative plasmids
highlights a possible joint dissemination of colistin and carbapenem
resistance in Brazilian hospitals, where KPC is already worrisome.
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