Recurrent Severe Preschool Wheeze: From Pre-Specified Diagnostic Labels to Underlying Endotypes

Polly F.M. Robinson,Sara Fontanella,Sachin Ananth,Aldara Martin-Alonso,James A. Cook,Daphne Kaya-de Vries,Luisa Polo Silveira,Lisa G. Gregory,Clare M. Lloyd,Louise Fleming,Andrew Bush,Adnan Custovic,Sejal Saglani

Recurrent Severe Preschool Wheeze: From Pre-Specified Diagnostic Labels to Underlying Endotypes

2021

Polly F.M. Robinson
Sara Fontanella
Sachin Ananth
Aldara Martin-Alonso
James A. Cook
Daphne Kaya-de Vries
Luisa Polo Silveira
Lisa G. Gregory
Clare M. Lloyd
Louise Fleming
Andrew Bush
Adnan Custovic
Sejal Saglani

Rationale: Preschool wheezing is heterogeneous, but the underlying mechanisms are poorly understood. Objectives: To investigate lower airway inflammation and infection in preschool children with di...

Keywords:

preschool wheeze
airway inflammation
Medicine
Pediatrics

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