Quality assessment of Succus Bambusae oral liquids based on GC-MS fingerprints and chemometrics

RATIONALE Succus Bambusae is consumed as a kind of herbal medicine and natural beverage in China. However, the current quality standards of Succus Bambusae are low and lack of safety indicators, which makes it difficult to effectively guarantee its quality. Therefore, it is of great significance to study the identification and quality control technology for the product. METHODS In this research, A set of qualitative and quantitative methods based on gas chromatography-mass spectrometry (GC-MS) was developed for the analysis of volatile components in Succus Bambusae oral liquid (SBOL). Combining GC-MS fingerprint analysis and related chemometrics algorithms, with similarity evaluation, Hotelling T2 and distance to Model X (DModX) as criteria, the quality consistency of different batches was evaluated, and the SBOL samples from different manufacturers were differentiated. RESULTS 29 volatile components were preliminarily identified from 40 batches of SBOL samples from 6 manufacturers, and 6 Q-markers (Quality Markers) for the SBOLs was disscussed and determined using GC-MS. The products from different manufacturers were distinguished using Chemometrics. CONCLUSIONS The results showed that the quality of the SBOL samples of different batches and different manufacturers fluctuated greatly, which suggested that the researches of raw materials and manufacturing techniques should be strengthened to improve the quality of SBOL and ensure its quality consistency.