Depresión en grupo de pacientes con epilepsias focales

Se estudiaron 130 pacientes con epilepsia focal sintomatica vistos previamente en consulta de neurologia, con el proposito de determinar la morbilidad oculta y las caracteristicas de la depresion en pacientes con epilepsia y compararlos con sujetos supuestamente sanos y pacientes con cefalea cronica. Se analizaron las variables multicausales de tipo biologico, psicosocial y medicamentoso. A los pacientes con epilepsia focal que asistian a consulta de epilepsia s e les aplico el cuestionario de epilepsia para determinar factores de riesgo y la escala de depresion CRS. Los grupos de depresion fueron comparados sobre la base de un grupo de factores biologicos, psicosociales y medicamentosos. Los datos se procesaron mediante los estadigrafos: Fisher, Chi-cuadrado, Odds Ratio, Mann Whitney y ANOVA. L a depresion se encontro en 73,64 por ciento de los pacientes con epilepsia, se compararon los indices de depresion con un grupo de 50 pacientes con cefalea y 50 controles sanos y se observo mas depresion en el grupo de pacientes con epilepsia para ANOVA F=6,02; p=0,034. Al analizar los factores causales en los pacientes con epilepsia se encontro que son significativos: las epilepsias postraumaticas, la elevada frecuencia de crisis, las epilepsias del lobulo temporal (ELT) y que empeora el pronostico con mas depresion severa en las crisis parciales complejas, el mal funcionamiento psicosocial y el uso de fenitoina asi como de las mezclas de farmacos antiepilepticos (FAE). One thousand thirty patients suffering from symptomatic focal epilepsy and previously teatred in neurology doctor's office were studied with the purpose to determine the hidden morbility and characteristic of depression in patients suffering from epilepsy and to establish a comparison with supposed healthy patients and patients suffering from chronic cephalgia. Medicinal, psicosocial and biologic multicausal variables were analyzed. A questionnaire about epilepsy's disease to determine factors of risk and the scale of depression CRS was applied to those patients who suffered from epilepsy and that were attended in an epilepsy doctor's office. The groups of patients suffering depression were compared among them using a group of medicinal, psicosocial and biologic factors. Data were processed by Fisher, Chi test, Odds Ratio, Mann Whitney and ANOVA stadigraphs. Depression was found in 73,64 per cent of patients suffering from epilepsy. Levels of depression were compared with a group of 50 – healthy patients and for ANOVA (F=6,02; p=0,034) on the group of patients suffering from epilepsy more depression was observed. Analyzing the causal factors on patients suffering from epilepsy; posttraumatic epilepsies, high frequency of crisis and epilepsy associated to the temporal lobule were found significant. Also (TLE) prognosis impairs with more severe depression in presence of complex partial crisis, psicosocial mis functioning and the use of fenitoine as well as antiepileptic drugs mixtures (FAE).