N,S co-doped carbon dots as a dual-functional fluorescent sensor for sensitive detection of baicalein and temperature

Abstract In this work, nitrogen and sulfur dual-doped CDs (N,S-CDs) were prepared via a facile one-pot hydrothermal method from citric acid and N -acetyl-L-cysteine with a high quantum yield (QY) of 49%. As-fabricated N,S-CDs had a size around 2.5 nm and exhibited excitation-independent emission and excellent luminescent properties. The fluorescent sensor based on the N,S-CDs showed a highly sensitive detection of baicalein with a detection limit (LOD) of 0.21 μmol L −1 in the linear range from 0.69 to 70.0 μmol L −1 . The fluorescence of the N,S-CDs could be effectively quenched by baicalein based on static quenching. In addition, the temperature sensor based on the synthesized N,S-CDs showed a good linear relationship between temperature and fluorescence (FL) intensity with a temperature range from 5 °C to 75 °C. Furthermore, the synthesized N,S-CDs were successfully applied to the measurement of baicalein in real samples. In a word, the N,S-CDs had great potential to be worked as fluorescence sensors to monitor the concentration of baicalein and temperature.