Enhancing Host-Cell Protein Detection in Protein Therapeutics Using HILIC Enrichment and Proteomic Analysis.

Qingyi Wang,Thomas R. Slaney,Wei Wu,Richard Ludwig,Li Tao,Anthony Leone

Enhancing Host-Cell Protein Detection in Protein Therapeutics Using HILIC Enrichment and Proteomic Analysis.

2020

Qingyi Wang
Thomas R. Slaney
Wei Wu
Richard Ludwig
Li Tao
Anthony Leone

Liquid chromatography-mass spectrometry (LC-MS)-based proteomics approaches have been widely used to identify residual host-cell proteins (HCPs) in support of process and product characterization f...

Keywords:

Chemistry
Hydrophilic interaction chromatography
Chromatography
Protein therapeutics
Mass spectrometry
Proteomics
protein detection

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