SYNTHESIS OF N, N3, 4-DIALKYLAMINO-1, 2, 5-OXADIAZOLES

N, N΄-3, 4-di(methylamino)-1, 2, 5-oxadiazole (1f) was prepared by dehydration of N, N΄-3, 4-di(methylamino)glyoxime (2f) in aqueous potassium hydroxid at 170-180 ˚C. Under similar conditions N, N΄-3, 4-di(benzylamino)-1, 2, 5-oxadiazole (1c) and N, N΄-3, 4-di(isopropylamino)-1, 2, 5-oxadiazole (1e) were not obtained, but, N, N΄-3, 4-di(ethylamino)-1, 2, 5-oxadiazole (1g) was appeared with small amount.