Pathogenesis of hypertensive pain syndrome

Comparative analysis of urea concentration in vitreous, vitreal fluid cavities and blood serum in patients with terminal painful glaucoma is performed based on laboratory data. Author proposes that pathogenesis of pain is related to "negative gradient of urea concentration", when urea concentration is higher in vitreous compared with blood serum. In the walls of ciliary processes where pain receptors are localized osmotic force causes tension provoking pain.