Original Article Efficacy of high-intensity focused ultrasound ablation for adenomyosis therapy and sexual life quality

Objective: The aim of this study was to evaluate the efficacy, safety and sexual life quality outcomes of ultrasound-guided high-intensity focused ultrasound (HIFU) ablations for the treatment of patients with symptomatic adenomyosis and uterine volumes >200 cm 3 . Methods: In our prospective clinical trial 47 patients with uterine vol- umes >200 cm 3 and symptomatic adenomyosis were treated with single treatment sessions of ultrasound-guided HIFU ablations. Beside uterus and adenomyosis lesion size reductions, outcome measures were symptom sever- ity score (SSS), visual analogue scale (VAS) of dysmenorrhea, female sexual function index (FSFI) scores and the incidence of complications. Results: In all 47 patients, the adenomyosis lesions sizes were significantly reduced 12 months after the interventions (P 200 cm 3 with symptomatic adenomyosis. Particularly maintaining the integrity of patients' uteri leads to significant FSFI score improvements, which were es - sentially reduced before the HIFU treatments.