Contribution of alternative complement pathway to delayed hemolytic transfusion reaction in sickle cell disease

2018 
Transfusion of red blood cells (RBC) remains a primary treatment modality in patients with sickle cell disease (SCD). Repeated exposure to alloantigens on transfused RBCs can lead to alloantibody formation that can increase the risk of delayed hemolytic transfusion reaction (DHTR).[1][1] The
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