BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ

Heeyoun Bunch,Jaehyeon Jeong,Keunsoo Kang,Doo Sin Jo,Anh T. Q. Cong,Deukyeong Kim,Donguk Kim,Dong-Hyung Cho,You Mie Lee,Benjamin P C Chen,Matthew J Schellenberg,Stuart K. Calderwood

BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ

2021

Heeyoun Bunch
Jaehyeon Jeong
Keunsoo Kang
Doo Sin Jo
Anh T. Q. Cong
Deukyeong Kim
Donguk Kim
Dong-Hyung Cho
You Mie Lee
Benjamin P C Chen
Matthew J Schellenberg
Stuart K. Calderwood

RNA polymerase II (Pol II)-dependent transcription in stimulus-inducible genes requires topoisomerase IIβ (TOP2B)-mediated DNA strand break and the activation of DNA damage response signalling in h...

Keywords:

DNA damage
Regulation of gene expression
Cell biology
DNA Strand Break
Biology
Gene
Topoisomerase
Transcription (biology)
RNA polymerase II
BRCA1-BARD1 complex

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