Theophylline is able to partially revert cachexia in tumour-bearing rats

Mireia Olivan,Jochen Springer,Sílvia Busquets,Anika Tschirner,Maite Figueras,Míriam Toledo,Cibely Cristine Fontes-Oliveira,Maria Inês Genovese,Paula Ventura da Silva,Angelica Sette,Francisco J. López-Soriano,Stefan D. Anker,Josep M. Argilés

Theophylline is able to partially revert cachexia in tumour-bearing rats

2012

Mireia Olivan
Jochen Springer
Sílvia Busquets
Anika Tschirner
Maite Figueras
Míriam Toledo
Cibely Cristine Fontes-Oliveira
Maria Inês Genovese
Paula Ventura da Silva
Angelica Sette
Francisco J. López-Soriano
Stefan D. Anker
Josep M. Argilés

Background and aims The aim of the present investigation was to examine the anti-wasting effects of theophylline (a methylxantine present in tea leaves) on a rat model of cancer cachexia.

Keywords:

Diabetes mellitus
Cancer
Endocrinology
Medicine
Internal medicine
Cachexia
Theophylline
Clinical nutrition
Gene expression
Cardiac function curve
Muscle tissue
Myocyte
Cell culture
Hyperthermia

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