Assessment of SMAD4, p53, and Ki-67 alterations as a predictor of liver metastasis in human colorectal cancer

Masayo Kawakami,Tatsuro Yamaguchi,Keiichi Takahashi,Hiroshi Matsumoto,Michiya Yasutome,Shinichiro Horiguchi,Yukiko K. Hayashi,Nobuaki Funata,Takeo Mori

Assessment of SMAD4, p53, and Ki-67 alterations as a predictor of liver metastasis in human colorectal cancer

2010

Masayo Kawakami
Tatsuro Yamaguchi
Keiichi Takahashi
Hiroshi Matsumoto
Michiya Yasutome
Shinichiro Horiguchi
Yukiko K. Hayashi
Nobuaki Funata
Takeo Mori

Purpose The liver is the most common site of metastasis in patients with colorectal cancer (CRC), and this is a determinant of the prognosis. However, no reliable molecular predictors of liver metastasis have yet been identified.

Keywords:

Ki-67
Colorectal cancer
General surgery
Metastasis
Medicine
Oncology
in patient
a determinant
Surgical oncology
Internal medicine

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