PITUITARY DWARFISM WITH DIABETES MELLITUS

Progress in clinical endocrinology depends largely upon the successful application of knowledge derived through extensive experimental animal research. It is generally assumed that there is a parallelism between the results obtained in man and those obtained in animals. There are instances, however, in which this corollary does not apply, and the reactions in man occur in an antagonistic or paradoxical manner as compared to those occurring in animals. The case which we herewith report, of pituitary dwarflsm with diabetes mellitus, is an example. There have been only a few such cases recorded in the literature. Sexton and Neuhoff (1) recently reported a somewhat similar case. We are presenting our case in the hope that it may stimulate further research and investigation, and ultimately solve this unexplained clinical phenomenon. Clinically, Goetsch, Cushing and Jacobson (2) early pointed out the presence of decreased sugar tolerance in cases of hyperpituitarism. Cushing (3) demonstrated that hypophysectomy...