Multiple coronary artery spasms triggering life-threatening ventricular arrhythmia associated with the radiofrequency ablation of ganglionated plexuses of the left atrium

Abstract We report a case of multiple coronary spasms leading to life-threatening ventricular arrhythmia, during left atrium (LA) ablation. Coronary artery spasm is a rare complication during radiofrequency catheter ablation of atrial fibrillation (AF). Previous reports mention that autonomic imbalance leads to coronary artery spasm and ST-segment elevation in the inferior leads, during trans-septal LA catheterization and AF ablation procedures. However, there are few reports detailing the association between ablation sites and changes in the electrocardiogram. We encountered transient ST-segment elevation and refractory ventricular arrhythmia, associated with coronary artery spasm, during radiofrequency ablation of ganglionated plexuses (superior surface of left and right atrium). Learning objective: Our case report shows that ablation of ganglionated plexus sites during pulmonary vein isolation, can induce ST-segment elevation in various leads, and cause multiple coronary spasms associated with refractory ventricular fibrillation. There is an inherent risk of multiple coronary spasms during catheter ablation of atrial fibrillation (AF), in patients with vasospastic angina. We recommend continuous intravenous infusion of nitroglycerin during ablation for AF to prevent coronary spasms in patients with vasospastic angina.>