Effect of Nifedipine on C-Reactive Protein Levels in the Coronary Sinus and on Coronary Blood Flow in Response to Acetylcholine in Patients With Stable Angina Pectoris Having Percutaneous Coronary Intervention

The effects of nifedipine on inflammation and endothelial function in the coronary circulation were studied in patients who had angina pectoris (n = 17). Long-term treatment with nifedipine (nifedipine CR, 20 mg/day for 4 months) decreased levels of C-reactive protein in the coronary sinus (from 0.35 ± 0.09 mg/dl to 0.07 ± 0.01 mg/dl, mean ± SEM, p