Caveolin-1 with tumour
2013
Caveolin are a family that proteins are highly conserved and located at the mammalian plasma membrane.They include four isoforms:Cav-1,Cav-2,Cav-3 and Cav-4.Caveolin proteins are implicated in endocytosis,lipid metabolism and cellular signaling.There is recent evidence that Cav-1 expression levels in tumour have been associated with tumour growth and metastasis,stromal car-1 expression downregulated have been also associated with mutli-tumor metastasis.
Key words:
Cav-1 ; Neoplasm metastasis ; Membrane proteins ; Growth ;
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