MicroRNAs shaping cellular reprogramming

Abstract Cellular reprogramming refers to the natural, malignant, and induced mechanisms by which a mature, fully differentiated cell backtracks along the cellular developmental landscape to an undifferentiated state. This process is marked by a cascade of distinct and sequentially orchestrated cellular events. miRNAs, a group of small non-coding RNAs, have emerged as functionally significant regulatory molecules in the process of cellular reprogramming, leaving their mark on every step of the reprogramming cascade. In this chapter, we have attempted to provide a bird’s eye view of the activity of these versatile molecules over the entire landscape of cellular reprogramming.