Contactless Monitoring of Pulse Rate and Eye Movement for Uveal Melanoma Patients Undergoing Radiation Therapy

Ensuring eye immobilization and monitoring vital signs are crucial for uveal melanoma patients undergoing radiation therapy (RT). However, current clinical use of an artificial way to observe eye movement and to assess vital signals relies on the use of contact sensors such as finger probe, which is toilsome and inefficient. In this paper, we integrated the contactless measurement methodology to simultaneously monitor the eye movement and pulse rate of patients. The proposed method was also applied to three recruited patients with uveal melanoma to measure the immobilization of eyeball and verify the accuracy of pulse rate detection. Based on the experimental results, the average error of eyeball measurement was 0.96 ± 0.66 mm (mean ± SD) and the average accuracy of pulse rate detection was 96.67%. The environmental illuminance of 2223.92 lx and 1454.59 lx was required to accurately measure eyeball movement and pulse rate, respectively. The use of camera-based contactless measurement under high-energy RT is feasible and has the potential to improve the current clinically used method.