Synthesis of [phenyl-2-3H]-travoprost: isopropyl ester prodrug of a selective prostaglandin FP receptor agonist
2001
A method for the preparation of tritium labeled travoprost, a new ocular hypotensive prostaglandin, is described. A highly selective catalytic deiodination has been identified which provides [phenyl-2-3H]-travoprost in a single synthetic step from 2′-iodo-travoprost. Copyright © 2001 John Wiley & Sons, Ltd.
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