Radioiodination and biological evaluation of candesartan as a tracer for cardiovascular disorder detection
2016
A procedure for radioiodination of valsartan with iodine-125 is carried out via an electrophilic substitution of hydrogen atom with the iodonium cation I + . All reaction parameters were studied to optimize the labeling conditions of valsartan and to obtain a maximum radiochemical yield (RCY) of the
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