Pemphigus in younger age group in Bangladeshi population

Background: Pemphigus is an uncommonly encountered bullous dermatoses among younger age group. The disease is characterized by autoimmune blistering disorder with remission and exacerbation. Bangladeshi population and highlight any differences and similarities with adult type. Patients and methods: A cross sectional study was conducted in the department of Dermatology and Venereology in 3 different hospitals in Bangladesh from 2006 to 2010.40 patients of age group 15-35 years. The patients, suffering from pemphigus diagnosed clinically and confirmed by histopathological examination of skin and DIF. The samples were selected purposively. Result: In this study, among the 40 cases, pemphipus vulgaris was found in 18 (60%) followed by pemphigus foliaceous 8 (26.67%), pemphigus erythematosus 2(6.67%) and 2(6.67%) paraneoplastic pemphigus. Conclusion: The study showed that among the thirty cases of the younger age group, the most common clinical variant is pemphigus vulgaris, mucosal involvement is the initial presentation and complications are mainly due to steroid therapy and all findings are similar with adult type.