Estimation of adhesion to antiretroviral coformulated 3 in 1

Introduction: In order to stimulate adherence to antiretrovirals and minimize the risks of viral mutations and resistance to these drugs, the Ministry of Health (MS) started providing the 3-in-1 drug, a co-formulation of tenofovir (300 mg), lamivudine (300 mg) and efavirenz (600 mg), which innovates by the use of a single daily tablet. Objective: Estimating the adherence to antiretroviral drugs in the first line of HIV treatment. Methods: Verification of the frequency of monthly patient returns to a dispensary of antiretroviral drugs provided by MS. Results: Patients treated with the 3-in-1 medication were more assiduous and returned 65% higher at the dispensary. Conclusion: The introduction of 3-in-1 confirms that the simplification of therapeutic schemes is a measure that facilitates adherence to treatment. This generates the expectation of keeping individuals in the first line of treatment longer, delaying the need to resort to other more expensive therapeutic lines, with a higher number of drugs and associated risks.