Gamma Knife Treatment for 124 Cases with Primary Trigeminal Neuralgia

Objective To Study and evaluate the effects of Gamma knife to treat ingprimary trigeminal neuralgia.Methods Between July 2002 and August 2010,124 patients with primary trigeminal neuralgia were treated with Gamma Knife.the chosen target was the root of trigeminal nerve just anterior to pons,The prescribed doses of the treatments were 70~90Gy.The patients were randomly divided into tow groups(80 Gy和80 Gy).After treatment,the patient were followed up for long time.Results 124 patients were followed up for 21 to 69 months with mean term of 32 months.The pain completely disappeared in 62 cases(50%),The pain basically disappeared in 31 cases(25%),the pain relief occurred in 23 cases(18.5%),and in 8 patient(6.5%) the pain was unchanged,efficiency 93.5%.There wasn't significant difference in pain relief between the tow groups(P0.01).Conclusion Treatment of primary trigeminal neuralgia with Gamma knife is effective and safe methods.75~80Gy radiation dose should be as most suitable.