Effects of mandibular condyle reconstruction by transport distraction osteogenesis on mandibular bone growth in goats
2008
Objective:To investigate the effects of mandibular condyle reconstruction by transport distraction osteogenesis on mandibular bone growth in goats.Methods:Sixteen 3-4 months juvenile male goats were used.The right condyles were extirpated with the articular discs reserved,and transport distraction osteogenesis was performed to reconstruct the mandibular condyle.The left mandibular condyles served as control.3D-CT examination was performed at different intervals.Two goats were randomly sacrificed respectively at 12,24 and 48 week for histological observation after completion of distraction.48 weeks after completion of distraction,the remaining goats were sacrificed for mandibular growth measurement.Results:The hemimandible of the distracted side exhibited similarities to the contralateral side except the larger neocondyles.There was no significant difference on the mandibular body and ramus between two sides.A well-organized fibrocartilage was seen at the neocondylar surface over time.Conclusion:A neocondyle reconstructed by transport distraction has the potential to grow under functional stimuli of the temporomandibular joint.
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