Bioceramic based scaffold for development ofbone tissue engineering: an overview

The development of biomaterials for scaffold and tissue engineering are in great advancement. Porous materials like bioceramic and polymer components for supporting bone tissue and cell growth are becoming an area of great interest in research [1]. Traditionally, biodegradable polymers have been used as scaffold material [2]. However, these materials are weak and non-osteoconductive. Polymer-based composite scaffolds containing bioceramics was then used to substitute the material. Thus, it is strongly believed that the bioceramic phase delivers the bioactivity and improves scaffolds strength. In addition to that, recently the engineering of biomaterial focused on the kind of material which can mimic both the mechanical and biological properties of real bone tissue matrix and this method known as biomimetic [3]. Other than that, there are also other recent challenges where scientists are also looking for biomaterials which can support the development of new blood vessels and large tissue formation. This paper was intended to demonstrate an overview of the current and potentially future development of composite bioceramic based scaffolds for bone tissue engineering.