RADIOTHERAPY IN KASABACH-MERRITT SYNDROME
1997
Abstract A male infant was born with a 1 × 3 cm reddish lesion under his umbilicus which enlarged within a month and was associated with consumptive coagulopathy. A diagnosis of Kasabach-Merritt syndrome (KMS) was made. After no response to prednisolone and interferon-α treatment, 8 Gy of radiotherapy (2 Gy. day −1 ) was applied. The clinical status improved and the lesion decreased by 95%. This case illustrates the potential use of radiotherapy in the management of KMS. Radiotherapy is a relatively simple and inexpensive treatment modality which should be considered for lesions that have failed to respond to medical treatment.
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