Effect of ginseng extract and ginsenosides on activity of cytochrome P450

Ginseng is the most famous Asian herb, and has been in medicinal use for thousands of years. It was used widely in Asia, Europe and America. In this review, authors introduce information on the effects of ginseng extract, preparations contenting ginseng, and ginsenosides on activities of cytochrome P450s, as well as drug-herb interaction according to the published research reports. It suggests that these results may be useful for understanding ginseng's clinical value and scientific and reasonable application of ginseng.