A highly sensitive colorimetric metalloimmunoassay based on copper-mediated etching of gold nanorods.

A highly sensitive colorimetric metalloimmunoassay with a detection limit of 0.15 ng ml−1 for human IgG based on copper-mediated etching of gold nanorods was proposed. The assay is more sensitive than traditional ELISA, electrochemical metalloimmunoassay and HRP mimic nanomaterial tag-based immunoassay.