Differential Gene Expression between Juvenile and Adult Dura Mater: A Window into What Genes Play a Role in the Regeneration of Membranous Bone

Background:Although reossification of large calvarial defects is possible in children, adults lack this tissue engineering capacity. In this study, the authors compared the differences in gene expression between juvenile and adult dura mater using a mouse cDNA microarray with 42,000 unique elements.