Langerhans Cell Histiocytosis on Fine Needle Aspiration Cytology: A Report of 2 cases and Review of Literature

Langerhans cell histiocytosis (LCH) also known as Histiocytosis X is a clinico-pathologic entity characterized by proliferation of Langerhans cells (LCs) throughout the body including the reticulo-endothelial system, bone& skin. LCs is currently considered as a distinct type of histiocytic cell, not primarily phagocytic in nature. Fine needle aspiration (FNA) is helpful in achieving a rapid and accurate diagnosis in an appropriate clinical and radiological setting. This can avoid unnecessary biopsy and guide the management especially where access to histopathology is limited. We report two cases of LCH in a 3 ½ year old & 6year old patients based on FNA from the site of swelling.