Sensibilidad antimicrobiana de cepas hipurato-negativas de Campylobacter spp. y de Helicobacter pullorum aisladas de enfermos con diarrea

espanolEl genero Campylobacter, tanto C. jejuni como algunas especies hipurato-negativas y generos relacionados, son la principal causa de gastroenteritis en nuestro entorno a lo largo de todo el ano. El objetivo del presente estudio es determinar la sensibilidad de cepas hipurato negativas de Campylobacter spp. y de Helicobacter pullorum aislados de heces diarreicas humanas. Se estudiaron 39 cepas de Campylobacter coli, dos de C. lari y cinco de Helicobacter pullorum identificadas por espectrometria de masas MALDI-TOF. La sensibilidad a amoxicilina-clavulanico, eritromicina, azitromicina, gentamicina, ciprofloxacino, levofloxacino, tetraciclina, tigeciclina y cloranfenicol se determino por E-test. La mayoria de las cepas de Campylobacter hipurato-negativos y H. pullorum estudiadas presentaron una elevada resistencia a las dos fluoroquinolonas probadas y a la tetraciclina. Por otro lado, todas las cepas fueron sensibles a amoxicilina-clavulanico, a tigeciclina y a cloranfenicol, mientras que la mayoria lo fueron a los macrolidos y a la gentamicina. EnglishC. jejuni as well as some hippurate-negative Campylobacter species and related diarrheagenic organisms, are the leading cause of gastroenteritis in our environment all throughout the year. The aim of the present study was to determine the sensitivity of hippurate-negative Campylobacter and Helicobacter pullorum strains isolated from the stools of patients with diarrhea. We tested 39 Campylobacter coli, two C. lari and five Helicobacter pullorum strains identified by mass spectrometry analysis. The sensitivity to amoxicillin-clavulanic acid, erytrhomycin, azithromycin, gentamicin, ciprofloxacin, levofloxacin, tetracycline, tigecycline and chloramphenicol was tested by E-test. Most hippurate-negative Campylobacter and H. pullorum isolates studied showed high resistance to tetracycline and to the two fluorquinolones tested. On the other side, all strains were sensitive to amoxicillin-clavulanic acid, tigecycline and chloramphenicol, while most of them were sensitive to both macrolides tested and to gentamicin.