Study on the Interaction Between 2, 6-bis(Benzimidazole-2-yl)PyridineAmino Aacid Lanthanum (III) Complex and DNA

2016 
The study on the interaction between 2, 6- bis(benzimidazole- 2- yl) pyridine amino acidlanthanum (Ⅲ) complex and deoxyribonucleic acid (DNA) was performed by the analysis methods ofultraviolet visible spectroscopy (UV), fluorescence spectroscopy, viscosimetry and cyclic voltammetry.The results indicated after interaction between the complex and DNA, all of the UV absorption intensity,fluorescence intensity and viscosity decreased with the binding constant of 1.1×10^5 L/mol. And the peakpotential of oxidation and reduction peaks did not change but the redox peak currents reduced from thecyclic voltammetry. All above indicated that the complex and DNA were combined through the partialintercalation and electrostatic binding.
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