Differences on metabolic behavior between intra and extrahepatic cholangiocarcinomas at 18 F-FDG–PET/CT: prognostic implication of metabolic parameters and tumor markers

Background and purpose Cholangiocarcinoma is an infrequent neoplasm barely studied with 18F-FDG–PET/CT. We evaluated the metabolic behavior of cholangiocarcinoma in PET/CT according to its location (intra or extrahepatic) and analyzed the relationship between metabolic parameters of the primary tumor and tumor markers (CA19-9 and CEA), determining their prognostic significance.