Influence of certain radioprotective preparations on the motor-evacuatory function of the gastrointestinal tract of healthy and irradiated rats

Cystamine, AET, tsistafos and 5-MOT, when administered in optimally protective doses orally, intraperitoneally and into the large intestine, retard the evacuation of contrasting material from the stomach by 4-8, 2, 5-6 and 2-3 times, respectively. Intraperitoneal administration to an animal, prior to irradiation, of cystamine during the first few hours increases the spasms of the pylorus, intensifies disturbance of the evacuatory function of the stomach, and later normalizes the functional state of the gastrointestinal tract.