A STUDY OF HISTOPATHOLOGICAL CHANGES IN VISCERA IN ALUMINIUM PHOSPHIDE POISONING

A prospective study to observe thehistopathological findings in Aluminium PhosphidePoisoning was undertaken on 70 autopsy cases conducted at S. S. Medical College, Rewa and associated Gandhi Memorial Hospital. Aluminium Phosphide poisoning hasbecome the commonest poisoning in cen tral India over the last few years. Aluminium Phosphide is a solid fumigant bulk grain preservative and is available in the market under various trade names like Celphos, Quickphos, Phostoxin, Phostek, Gastoxin, Zedesa, Li Fumesets. It is marketed either i n Table t or pellet form. Mortality is high as mechanism of action is not clearly understood and no specific antidote is available against this poison. Samples of tissues fromliver, lungs, kidneys and spleen were preserved in 10% Formal Saline, processed fo r histopathology, stained by Haematoxylin and Eosin method and studied microscopically. Observations made in similar previous studies are compared with findings of present study and discussed.