Speckle noise removal based on structural convolutional neural networks with feature fusion for medical image

Abstract Application of convolutional neural networks (CNNs) for image additive white Gaussian noise (AWGN) removal has attracted considerable attentions with the rapid development of deep learning in recent years. However, the work of image multiplicative speckle noise removal is rarely done. Moreover, most of the existing speckle noise removal algorithms are based on traditional methods with human priori knowledge, which means that the parameters of the algorithms need to be set manually. Nowadays, deep learning methods show clear advantages on image feature extraction. Multiplicative speckle noise is very common in real life images, especially in medical images. In this paper, a novel neural network structure is proposed to recover noisy images with speckle noise. Our proposed method mainly consists of three subnetworks. One network is rough clean image estimate subnetwork. Another is subnetwork of noise estimation. The last one is an information fusion network based on U-Net and several convolutional layers. Different from the existing speckle denoising model based on the statistics of images, the proposed network model can handle speckle denoising of different noise levels with an end-to-end trainable model. Extensive experimental results on several test datasets clearly demonstrate the superior performance of our proposed network over state-of-the-arts in terms of quantitative metrics and visual quality.