Postoperative early enteral nutrition therapy with long peptide mixture for gastric cancer patients:a clinical control study

Objective To study the efficacy of postoperative early enteral nutrition(EN)therapy with long peptide mixture in gastric cancer patients receiving distal subtotal gastrectomy.Methods A total of 70patients with gastric cancer were randomly divided into experimental group(n=35)and control group(n=35)after distal subtotal gastrectomy.The experimental group received early enteral nutrition with long peptide mixture postoperatively(NEN group)and the control group received early enteral nutrition with glucose saline postoperatively(GEN group).Results There were no significant differences in the recovery time of intestinal peristalsis or ventilation time between the two groups after treatment.Significant differences were found between the two groups regarding the symptoms of diarrhea and vomiting(P=0.048,P=0.000).The hospitalization time and total cost of hospitalization were not significantly different between the two groups.The level of prealbumin in the experimental group was significantly higher than those in the control group on the fourth and seventh days after operation(P=0.000,P=0.000);moreover,compared with the control group,the experimental group had significantly higher IgGlevel on the fourth day and seventh day after operation(P=0.000 6,P=0.000 8),and IgM level was significantly higher than that in the control group on the seventh day after operation(P=0.000 1).Conclusion Postoperative early enteral nutrition with long peptide mixture can induce obvious gastrointestinal irritation symptoms in gastric cancer patients receiving distal subtotal gastrectomy,but it does not greatly increase the hospitalization time or cost,and can rapidly improve the nutrition and immune state of patients.